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A recurrent giant cell tumor of bone treated with denosumab

Nicola Stadler, Thomas Fingernagel, Stefan G. Hofstaetter, Klemens Trieb
  • Nicola Stadler
    Department of Orthopaedics, Klinikum Wels-Grieskirchen, Wels, Austria
  • Thomas Fingernagel
    Department of Orthopaedics, Klinikum Wels-Grieskirchen, Wels, Austria
  • Stefan G. Hofstaetter
    Department of Orthopaedics, Klinikum Wels-Grieskirchen, Wels, Austria

Abstract

Although the giant cell tumor of bone is generally classified as a benign tumor it can rarely metastasize and has a potential risk of local recurrence. We want to report about a female patient who suffered from a recurrence of a giant cell tumor of bone after the implantation of a total endoprosthesis of the knee joint. We have treated her with denosumab, which is a receptor activator of nuclear factor kappa-B ligand inhibitor. In this case report we want to present a new option to treat this kind of neoplasm.

Keywords

bone, denosumab, tumor.

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Submitted: 2014-08-06 15:08:07
Published: 2015-02-10 16:08:01
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Copyright (c) 2015 Nicola Stadler, Thomas Fingernagel, Stefan G. Hofstaetter, Klemens Trieb

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