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Acute disseminated intravascular coagulation following surgical resection of a myeloid sarcoma in a 57-year-old male

Rohan Paul, David Morgan, Michael Levitt, Ross Baker
  • David Morgan
    St John of God Hospital, Subiaco, WA, Australia
  • Michael Levitt
    St John of God Hospital, Subiaco, WA, Australia
  • Ross Baker
    Royal Perth Hospital, Murdoch University, Perth, WA, Australia

Abstract

Myeloid sarcoma is a rare extramedullary tumour consisting of immature myeloid cells. It can arise at any anatomical location and often develops in the bowel. This report describes a case of severe acute disseminated intravascular coagulation (DIC) with multi-organ failure occurring in a 57-year-old man with chronic myelomonocytic leukaemia during bowel resection for newly diagnosed adenocarcinoma of the sigmoid colon. Histopa thology however revealed a differentiating myeloid sarcoma encompassing a well-differentiated adenocarcinoma. This is the first documented case of acute DIC to be triggered following surgical manipulation of myeloid sarcoma.

Keywords

myeloid sarcoma, disseminated intravascular coagulation, leukaemic transformation.

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Submitted: 2012-02-07 07:20:55
Published: 2012-05-18 18:49:26
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Copyright (c) 2012 Rohan Paul, David Morgan, Michael Levitt, Ross Baker

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