Bone marrow abnormalities detected by magnetic resonance imaging as initial sign of hematologic malignancies

  • Ida Sofie Grønningsæter Institute of Clinical Science, University of Bergen; Department of Medicine, Haukeland University Hospital, Norway.
  • Aymen Bushra Ahmed Department of Medicine, Haukeland University Hospital, Norway.
  • Nils Vetti Institute of Clinical Science, University of Bergen; Radiological Department, Haukeland University Hospital, Norway.
  • Silje Johansen Department of Medicine, Haukeland University Hospital, Norway.
  • Øystein Bruserud Institute of Clinical Science, University of Bergen; Department of Medicine, Haukeland University Hospital, Norway.
  • Håkon Reikvam | Hakon.Reikvam@med.uib.no Institute of Clinical Science, University of Bergen; Department of Medicine, Haukeland University Hospital, Norway.

Abstract

The increasing use of radiological examination, especially magnetic resonance imaging (MRI), will probably increase the risk of unintended discovery of bone marrow abnormalities in patients where a hematologic disease would not be expected. In this paper we present four patients with different hematologic malignancies of nonplasma cell types. In all patients the MRI bone marrow abnormalities represent an initial presentation of the disease. These case reports illustrate the importance of a careful diagnostic follow-up without delay of patients with MRI bone marrow abnormalities, because such abnormalities can represent the first sign of both acute promyelocytic leukemia as well as other variants of acute leukemia.

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Published
2018-06-07
Section
Case Reports
Keywords:
Leukemia, magnetic resonance imaging, bone marrow disease.
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How to Cite
Grønningsæter, I. S., Ahmed, A. B., Vetti, N., Johansen, S., Bruserud, Øystein, & Reikvam, H. (2018). Bone marrow abnormalities detected by magnetic resonance imaging as initial sign of hematologic malignancies. Clinics and Practice, 8(2). https://doi.org/10.4081/cp.2018.1061