Assessing vitamin D and mammographic breast density in Alaskan women

  • Narjust Duma | nduma@wisc.edu Division of Hematology, Medical Oncology and Palliative Care, University of Wisconsin, Madison, WI, United States. https://orcid.org/0000-0002-7814-1773
  • Ivana Croghan Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States.
  • Sarah Jenkins Department of Health Sciences Research, Mayo Clinic, Rochester, MN, United States.
  • Celine Vachon Department of Health Sciences Research, Mayo Clinic, Rochester, MN, United States.
  • Loni Neal Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States. https://orcid.org/0000-0001-6545-9507
  • Karthik Ghosh Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States. https://orcid.org/0000-0002-8356-0980
  • Sandhya Pruthi Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States.

Abstract

Vitamin D deficiency and high breast density may be associated with increased breast cancer risk. We examined a possible association between vitamin D levels and mammographic breast density in a population of Alaskan women. Patients seen in the Mayo Clinic-Alaska Native Medical Center telemedicine program from December 2014 to December 2017 were enrolled in the study. Pearson correlation was used to estimate the association between mammographic breast density and vitamin D levels. Of the 33 women enrolled, 70% of women self-identified as American Indian/Alaskan Native, 12% as White, 6% as Native Hawaiian/Pacific Islander and 12% as other. Nineteen (58%) participants were taking vitamin D supplementation. No correlation was identified between breast density and serum vitamin D levels overall (correlation= –0.03). Larger studies controlling for vitamin supplementation are needed, as this association could potentially impact breast cancer rates in populations at risk for vitamin D deficiency.

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Published
2020-10-15
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Section
Brief Reports
Keywords:
Breast density, vitamin D, Alaskan native, telemedicine.
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How to Cite
Duma, N., Croghan, I., Jenkins, S., Vachon, C., Neal, L., Ghosh, K., & Pruthi, S. (2020). Assessing vitamin D and mammographic breast density in Alaskan women. Clinics and Practice, 10(4). https://doi.org/10.4081/cp.2020.1253