A recurrent giant cell tumor of bone treated with denosumab

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Nicola Stadler
Thomas Fingernagel
Stefan G. Hofstaetter
Klemens Trieb *
(*) Corresponding Author:
Klemens Trieb | klemens.trieb@klinikum-wegr.at

Abstract

Although the giant cell tumor of bone is generally classified as a benign tumor it can rarely metastasize and has a potential risk of local recurrence. We want to report about a female patient who suffered from a recurrence of a giant cell tumor of bone after the implantation of a total endoprosthesis of the knee joint. We have treated her with denosumab, which is a receptor activator of nuclear factor kappa-B ligand inhibitor. In this case report we want to present a new option to treat this kind of neoplasm.

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