Hydrocephalus, a rare manifestation of sarcoidosis

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Johan M. van Rooijen
Gerritje S. Mijnhout *
Tom T.A. Aalders
R.B.J. de Bondt
(*) Corresponding Author:
Gerritje S. Mijnhout | g.s.mijnhout@isala.nl


A 36-week-pregnant woman developed a symptomatic hydrocephalus. Chest imaging showed bihilar lymphadenopathy and histological examination of a mediastinal lymph node revealed non-caseating granulomas. After delivery, her neurologic complaints progressed. Placement of a ventriculoperitoneal drain (VPD) did not reduce the symptoms. However, steroids resulted in rapid disappearance of the hydrocephalus. Hydrocephalus is a very rare manifestation of sarcoidosis. The diagnosis relies on the ability of clinicians to recognize this disorder. This case shows how a difference in opinion of the several specialists involved can lead to a delay in diagnosis and treatment.

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