Multiple pulmonary nodules: a complex case of Wegener’s granulomatosis

  • Mariya Apostolova Conemaugh Memorial Medical Center, Department of Internal Medicine, Johnstown, PA, United States.
  • Mahmoud Shoib Conemaugh Memorial Medical Center, Department of Internal Medicine, Johnstown, PA, United States.
  • Samer Nasser | nsamer54@gmail.com Conemaugh Memorial Medical Center, Department of Internal Medicine, Johnstown, PA, United States.

Abstract

Wegener’s granulomatosis is a granulomatous vasculitis that can present with a wide spectrum of clinical manifestations. This disease entity predominantly affects the respiratory tract and the kidneys. Two forms of Wegener’s granulomatosis have been recognized: systemic and limited. It has not been established if the two forms represent separate disease entities or different stages of the same condition. In the limited form of Wegener’s granulomatosis there is no immediate threat to the function of vital organs and there is no evidence of glomerulonephritis. Environmental factors that could serve as triggers for the activation of Wegener’s granulomatosis have not been clearly defined. We report a case of a 78- year old male who was found to have bilateral pulmonary nodules on pre-operative chest X-ray and was diagnosed with the limited form of Wegener’s granulomatosis. The patient developed Clostridium difficile infection, and shortly after that active glomerulonephritis, a manifestation of systemic Wegener’s granulomatosis.

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Published
2013-04-12
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Section
Case Reports
Keywords:
Wegener’s granulomatosis, vasculitis, pulmonary nodules, renal failure.
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How to Cite
Apostolova, M., Shoib, M., & Nasser, S. (2013). Multiple pulmonary nodules: a complex case of Wegener’s granulomatosis. Clinics and Practice, 3(1), e14. https://doi.org/10.4081/cp.2013.e14