Clinics and Practice 2019-08-20T23:06:16+02:00 Francesca Baccino Open Journal Systems <p><strong>Clinics and Practice</strong>&nbsp;[ISSN 2039-7283] is a peer-reviewed, Open Access, online-only journal that publishes both&nbsp;<em>brief reports</em>&nbsp;and&nbsp;<em>case reports</em>&nbsp;in all areas of clinical medicine. Our journal would welcome any interesting description of patients, procedures and treatment in any condition or disease disease that can contribute to develop scientifically rigorous and clinically meaningful practice methods. <br><strong>Clinics and Practice</strong> aims at creating an innovative, rapid and collaborative background intended to help healthcare professionals finding the latest advances to answer the most pressing questions coming from the medicine/patients relationship.</p> Giant aggressive forehead tumor: A 15-year follow-up 2019-08-20T23:06:16+02:00 Raymond Challita Said Halabi <p>Proliferating trichilemmal tumors are rare tumors that originate from adnexal structures specifically from the outer root sheaths of hair follicles. These tumors can be benign or malignant. We report a rare case of an aggressive giant forehead trichilemmal tumor that was paradoxically benign on pathology. It was surgically excised and followed-up for 15 years.</p> 2019-08-02T10:33:18+02:00 ##submission.copyrightStatement## Cardiac papillary fibroelastoma of a bicuspid aortic valve in an adolescent: A case report 2019-08-20T23:06:15+02:00 Sarah Dénes Benoît Daron Marie Behaeghe Marie-Christine Seghaye <p>Cardiac papillary fibroelastomas (CPFE) are exceptional primary benign cardiac tumours, affecting the heart valves. We report here the case of a 15-year-old boy in whom echocardiography performed for non-specific chest pain during follow-up for bicuspid aortic valve showed as accidental finding the presence of a round mobile mass without stalk attached on the inferior side of the aortic valve. The mass did not cause any outflow tract obstruction or aortic insufficiency. ECG-gated cardiac computed tomography and magnetic resonance imaging allowed to suspect CPFE. Although the patient was asymptomatic, open cardiac surgery with elective surgical resection of the tumour were performed to avoid systematic emboli. Histology confirmed the diagnosis of CPFE. This is an exceptional case of acquired CPFE in a young patient with bicuspid aortic valve. Due the risk of systemic embolization, aortic- or coronary ostium obstruction, elective excision of such lesions is recommended.</p> 2019-08-07T16:25:18+02:00 ##submission.copyrightStatement## An unusual infection in an immunocompetent male of a non-endemic area: Lessons from a vacation 2019-08-20T23:06:14+02:00 Ritesh Neupane Munish Sharma Divakar Sharma Rajeev Thachil Mahesh Krishnamurthy Gerald Lowman <p>Primary pulmonary histoplasmosis is found worldwide, and is particularly endemic in some areas of the North America, usually those surrounding the Ohio and Mississippi river valleys. It is not common in the East Coast of the United States, and is in fact, reportable in Pennsylvania. It has been rarely described in immunocompetent individuals residing in a non-endemic region. We present a case of a previously healthy middle-aged male, a Pennsylvania resident, who presented with mid-sternal chest discomfort, fatigue, chills and mild shortness of breath, and was diagnosed with primary pulmonary histoplasmosis.</p> 2019-08-09T13:58:53+02:00 ##submission.copyrightStatement##